Research Grade Berahyaluronidase Alfa (HW825016)

Name: Research Grade Berahyaluronidase Alfa
Brand: abinScience
SKU: HW825016
Price: 352 USD
Availability: InStock

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Overview

Catalog No.	HW825016
Description	Berahyaluronidase Alfa (HW825016) is a research-grade recombinant antibody targeting Hyaluronidase PH-20. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Functional assay, Research in vivo
Clonality	Monoclonal
Isotype	Human hyaluronidase isozyme-5/HYAL5 fragment engineered variant with the structural domain replaced by the corresponding region of human hyaluronidase isozyme-1/HYAL1.
Expression system	Mammalian cells
Target	Hyaluronidase PH-20, Sperm surface protein PH-20, HYAL3, Sperm adhesion molecule 1, PH20, SPAM1, Hyal-PH20, Hyaluronoglucosaminidase PH-20
Endotoxin level	< 10 EU/mg
Purity	>95% purity as determined by SDS-PAGE.
Purification	Purified by Nickel column.
Accession	P38567
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	2636716-20-4
Background	Hyaluronidase PH-20 (SPAM1) is a ~57 kDa protein. Involved in sperm-egg adhesion. Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg before reaching the zona pellucida. The cumulus cells are embedded in a matrix containing hyaluronic acid which is formed prior to ovulation. This protein aids in penetrating the layer of cumulus cells by digesting hyaluronic acid.
Note	For research use only. Not suitable for clinical or therapeutic use.

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Research Grade Berahyaluronidase Alfa.pdf

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Research Grade Berahyaluronidase Alfa (HW825016)

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