Anti-Human CEACAM‑8/CD66b Reference Antibody (Besilesomab, RUO) (HB202016)

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100ug
1mg

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Overview

Catalog No.	HB202016
Description	Besilesomab (HB202016) is a research-grade recombinant antibody targeting CD67. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Mouse
Isotype	IgG1-kappa
Expression system	Mammalian Cells
Clonality	Monoclonal
Target	CD67 antigen, Carcinoembryonic antigen CGM6, Carcinoembryonic antigen-related cell adhesion molecule 8, CGM6, CD66b, Non-specific cross-reacting antigen NCA-95, CEACAM8
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P31997
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	BW250/183, 537694-98-7
Background	Cell adhesion molecule CEACAM8 (CD66b) is a ~38 kDa protein. Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner. Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Heterophilic interaction with CEACAM8 occurs in activated neutrophils. 1. Kuroki, M. et al. (2001) Journal of leukocyte biology 70, 543-50. PMID: 11590190 2. Oikawa, S. et al. (1991) The Journal of biological chemistry 266, 7995-8001. PMID: 2022629 3. Yamanaka, T. et al. (1996) Protein expression and purification 7, 438-46. PMID: 8776764
Note	For research use only. Not suitable for clinical or therapeutic use.

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Bioactivity

Detects CD66b/CEACAM8 in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Besilesomab

References

Datasheet

Anti-Human CEACAM‑8/CD66b Reference Antibody (Besilesomab, RUO).pdf

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Recombinant Proteins

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Anti-Human CEACAM‑8/CD66b Reference Antibody (Besilesomab, RUO) (HB202016)

Overview

Images

References

Datasheet

SDS

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