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Anti-Human Stabilin-1/FEEL1 Reference Antibody (Bexmarilimab, RUO) (HP617016)

Anti-Human Stabilin-1/FEEL1 Reference Antibody (Bexmarilimab, RUO)
Anti-Human Stabilin-1/FEEL1 Reference Antibody (Bexmarilimab, RUO)
Anti-Human Stabilin-1/FEEL1 Reference Antibody (Bexmarilimab, RUO)
Anti-Human Stabilin-1/FEEL1 Reference Antibody (Bexmarilimab, RUO)
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  • Overview

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  • Datasheet

  • SDS

Overview
Catalog No.HP617016
Description
Bexmarilimab (HP617016) is a research-grade recombinant antibody targeting MS-1 antigen. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHuman
IsotypeIgG4-kappa
Expression system Mammalian cells
Clonality Monoclonal
Target MS-1 antigen, STAB1, FEEL-1, FEEL1, Stabilin-1, KIAA0246, Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q9NY15
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Stabilin-1 (STAB1) is a ~275 kDa protein. Acts as a scavenger receptor for acetylated low density lipoprotein. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. When inhibited in endothelial tube formation assays, there is a marked decrease in cell-cell interactions, suggesting a role in angiogenesis. Involved in the delivery of newly synthesized CHID1/SI-CLP from the biosynthetic compartment to the endosomal/lysosomal system.

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Human Stabilin-1/FEEL1 Reference Antibody (Bexmarilimab, RUO)

    Bioactivity

    SEC-HPLC detection for Research Grade Bexmarilimab.

  • Anti-Human Stabilin-1/FEEL1 Reference Antibody (Bexmarilimab, RUO)

    SDS-PAGE

    SDS-PAGE for Anti-Human Stabilin-1/FEEL1 Reference Antibody (Bexmarilimab, RUO)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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