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Anti-Canine CD20 Reference Antibody (Blontuvetmab, RUO) (CY257016)

Anti-Canine CD20 Reference Antibody (Blontuvetmab, RUO)
Anti-Canine CD20 Reference Antibody (Blontuvetmab, RUO)
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  • Overview

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  • Datasheet

  • SDS

Overview
Catalog No.CY257016
Description
Blontuvetmab (CY257016) is a research-grade recombinant antibody targeting CD20. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityCanine
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesCanine
IsotypeIgG2-kappa-lambda
Expression system Mammalian cells
Clonality Monoclonal
Target CD20/MS4A1
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q3C2E2
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesAT-004, VT-007, 1608112-78-2
Background

B-lymphocyte antigen CD20 (MS4A1) is a ~33 kDa protein. B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR. CD20 is the therapeutic target of rituximab (MabThera) and obinutuzumab (Gazyva).

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Canine CD20 Reference Antibody (Blontuvetmab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Blontuvetmab.

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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