Anti-Human IL-4R alpha Reference Antibody (Camtarkibart, RUO) (HB732196)

Name: Anti-Human IL-4R alpha Reference Antibody (Camtarkibart, RUO)
Brand: abinScience
SKU: HB732196
Price: 176 USD
Availability: InStock

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Overview

Catalog No.	HB732196
Description	camtarkibart (HB732196) is a research-grade recombinant antibody targeting CD124. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research.
Species reactivity	Human
Applications	ELISA, FACS, Functional assay
Host species	Human
Isotype	IgG4, kappa
Target	CD124/IL4R/IL-4Rα
Endotoxin level	< 10 EU/mg
Purity	>95% as determined by SDS-PAGE
Accession	P24394
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CAS: 3031358-44-5
Background	Interleukin-4 receptor subunit alpha is a ~89 kDa protein. Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2. 1. Andrews, AL. et al. (2006) The Journal of allergy and clinical immunology 118, 858-65. PMID: 17030238
Note	For research use only.