Anti-Human Von Willebrand Factor Reference Antibody (Caplacizumab, RUO) (HY255016)

Name: Anti-Human Von Willebrand Factor Reference Antibody (Caplacizumab, RUO)
Brand: abinScience
SKU: HY255016
Price: 176 USD
Availability: InStock

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Overview

Catalog No.	HY255016
Description	Caplacizumab (HY255016) is a research-grade recombinant antibody targeting von Willebrand antigen II. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	VH-VH
Expression system	Mammalian cells
Clonality	Monoclonal
Target	von Willebrand antigen II, von Willebrand factor, F8VWF, vWF, VWF
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P04275
Form	Liquid
Storage buffer	20 mM citric acid, 6.2% sucrose, 0.01% Tween80 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	ALX-0081, PMP12A2h1-linkerAAA-PMP12A2h1, caplacizumab-yhdp, 915810-67-2
Background	von Willebrand factor (VWF) is a ~309 kDa protein. Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
Note	For research use only. Not suitable for clinical or therapeutic use.