Anti-Human CCL17/TARC Reference Antibody (Denrakibart, RUO) (HV615016)

Name: Anti-Human CCL17/TARC Reference Antibody (Denrakibart, RUO)
Brand: abinScience
SKU: HV615016
Price: 176 USD
Availability: InStock

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Overview

Catalog No.	HV615016
Description	denrakibart (HV615016) is a research-grade recombinant antibody targeting CCL17/TARC. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG2, Kappa
Species	Human
Clonality	Monoclonal
Target	CCL17/TARC
Endotoxin level	< 10 EU/mg
Purity	>95% as determined by SDS-PAGE.
Accession	Q92583
Form	Liquid
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	2922866-66-6
Background	C-C motif chemokine 17 (CCL17/TARC) is a ~10 kDa protein. Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Therefore plays an important role in a wide range of inflammatory and immunological processes. Acts by binding to CCR4 at T-cell surface. Mediates GM-CSF/CSF2-driven pain and inflammation. In the brain, required to maintain the typical, highly branched morphology of hippocampal microglia under homeostatic conditions. 1. Imai, T. et al. (1996) The Journal of biological chemistry 271, 21514-21. PMID: 8702936 2. Imai, T. et al. (1997) The Journal of biological chemistry 272, 15036-42. PMID: 9169480 3. Garlisi, CG. et al. (1999) European journal of immunology 29, 3210-5. PMID: 10540332 4. Achuthan, A. et al. (2016) The Journal of clinical investigation 126, 3453-66. PMID: 27525438
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE for Research Grade denrakibart

References

Datasheet

Anti-Human CCL17/TARC Reference Antibody (Denrakibart, RUO).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

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Anti-Human CCL17/TARC Reference Antibody (Denrakibart, RUO) (HV615016)

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References

Datasheet

SDS

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