Anti-Ganglioside GD2 Reference Antibody (Donitabart, RUO) (HP115026)

Name: Anti-Ganglioside GD2 Reference Antibody (Donitabart, RUO)
Brand: abinScience
SKU: HP115026
Price: 370 USD
Availability: InStock

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Overview

Catalog No.	HP115026
Species reactivity	General
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Chimeric
Clonality	Monoclonal
Isotype	IgG1-kappa
Biological activity	Ganglioside GD2 is associated with tumor development and malignant phenotypes, and its mechanism of action involves enhancing cell proliferation, motility, migration, adhesion and invasion, with specific effects depending on tumor type [1].
Expression system	Mammalian cells
Target	Ganglioside GD₂, GalNAcβ1, 4(Neu5Acα2, 8)(Neu5Acα2, 03)Galβ1
Endotoxin level	< 10 EU/mg
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	CAS: 65988-71-8, ChEBI: 89637
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CAS: 2888594-15-6
References	1. Nazha B, et al. Disialoganglioside GD2 Expression in Solid Tumors and Role as a Target for Cancer Therapy. Front Oncol. 2020;10:1000. Published 2020 Jul 7. [HP115026] 2. Erber R, et al. Variable Expression of the Disialoganglioside GD2 in Breast Cancer Molecular Subtypes. Cancers (Basel). 2021;13(21):5577. Published 2021 Nov 8. [HP115026]
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE for Research Grade Donitabart.

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Datasheet

Anti-Ganglioside GD2 Reference Antibody (Donitabart, RUO).pdf

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Anti-Ganglioside GD2 Reference Antibody (Donitabart, RUO) (HP115026)

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Datasheet

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