

| Catalog No. | HC100016 |
|---|---|
| Description |
eflumenibep alfa (HC100016) is a research-grade recombinant antibody targeting SPINK2.
Highlights
|
| Species reactivity | Human |
| Applications | Functional assay |
| Clonality | Monoclonal |
| Isotype | SPINK2-Fc |
| Expression system | Mammalian cells |
| Nature | Recombinant |
| Target | SPINK2 |
| Endotoxin level | < 10 EU/mg as determined by LAL method. |
| Purity | >95% as determined by SDS-PAGE. |
| Accession | P20155 |
| Storage buffer | 0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | CAS: 2418159-10-9 |
| Background | Serine protease inhibitor Kazal-type 2 is a ~9 kDa protein. As a strong inhibitor of acrosin, it is required for normal spermiogenesis. It probably hinders premature activation of proacrosin and other proteases, thus preventing the cascade of events leading to spermiogenesis defects. May be involved in the regulation of serine protease-dependent germ cell apoptosis. It also inhibits trypsin. 1. Kherraf, ZE. et al. (2017) EMBO molecular medicine 9, 1132-1149. PMID: 28554943 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
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