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Research Grade eflumenibep alfa (HC100016)

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Overview
Catalog No.HC100016
Description
eflumenibep alfa (HC100016) is a research-grade recombinant antibody targeting SPINK2.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
Species reactivityHuman
ApplicationsFunctional assay
ClonalityMonoclonal
IsotypeSPINK2-Fc
Expression system Mammalian cells
Nature Recombinant
Target SPINK2
Endotoxin level < 10 EU/mg as determined by LAL method.
Purity >95% as determined by SDS-PAGE.
Accession P20155
Storage buffer 0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesCAS: 2418159-10-9
Background

Serine protease inhibitor Kazal-type 2 is a ~9 kDa protein. As a strong inhibitor of acrosin, it is required for normal spermiogenesis. It probably hinders premature activation of proacrosin and other proteases, thus preventing the cascade of events leading to spermiogenesis defects. May be involved in the regulation of serine protease-dependent germ cell apoptosis. It also inhibits trypsin.

1. Kherraf, ZE. et al. (2017) EMBO molecular medicine 9, 1132-1149. PMID: 28554943
Note For research use only. Not suitable for clinical or therapeutic use.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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