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Research Grade efpixileukin alfa (HX061096)

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Overview
Catalog No.HX061096
Description
efpixileukin alfa (HX061096) is a research-grade recombinant antibody targeting IL2RB.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
ApplicationsFunctional assay
ClonalityMonoclonal
IsotypeIL2-Fc
Target IL2RB
Endotoxin level < 10 EU/mg
Purity >95% as determined by SDS-PAGE
Purification Protein A/G purified from cell culture supernatant.
Accession P14784
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesCAS: 2996895-52-2
Background

Interleukin-2 receptor subunit beta is a ~61 kDa protein. Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15.

1. Ratthé, C. et al. (2004) Journal of leukocyte biology 76, 162-8. PMID: 15123770
2. Zhang, Z. et al. (2019) The Journal of experimental medicine 216, 1311-1327. PMID: 31040185
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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