Research Grade Efruxifermin (HV802046)

Name: Research Grade Efruxifermin
Brand: abinScience
SKU: HV802046
Price: 192 USD
Availability: InStock

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Overview

Catalog No.	HV802046
Description	Efruxifermin (HV802046) is a research-grade recombinant antibody targeting Fibroblast growth factor 21. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Isotype	Human IgG1 Fc domain linked to a modified human FGF21.
Expression system	Mammalian cells
Target	Fibroblast growth factor 21, FGF-21, FGF21, UNQ3115/PRO10196
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q9NSA1
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	2375240-92-7
Background	Fibroblast growth factor 21 (FGF21) is a ~22 kDa protein. Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. Regulates systemic glucose homeostasis and insulin sensitivity.
Note	For research use only. Not suitable for clinical or therapeutic use.