Anti-Human PD-L1&4-1BB/TNFRSF9/CD137&CD3&CD19 Multispecific Reference Antibody (Emfizatamab, RUO) (HB996096)

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Spec:

100ug
1mg

Number:

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SDS

Overview

Catalog No.

HB996096

Description

Emfizatamab (HB996096) is a research-grade recombinant antibody targeting CD19. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

Species reactivity

Human

Applications

ELISA, Bioactivity: FACS, Functional assay, Research in vivo, WB

Isotype

(scFv-kappa-heavy)-G1_L-kappa-(scFv-heavy-kappa)-(scFv-heavy-kappa)

Expression system

Mammalian Cells

Clonality

Monoclonal

Tested applications

Target

CD19, Differentiation antigen CD19, T-cell surface antigen Leu-12, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, B7-H1, Programmed cell death 1 ligand 1, PDCD1 ligand 1, PDCD1L1, B7 homolog 1, PDCD1LG1, PDL1, hPD-L1, Programmed death ligand 1, B7H1, PD-L1, CD274, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain, Tumor necrosis factor receptor superfamily member 9, CD137, 4-1BB ligand receptor, CDw137, TNFRSF9, T-cell antigen ILA, T-cell antigen 4-1BB homolog, ILA

Endotoxin level

Please contact the lab for this information.

Purity

>95% purity as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P15391 & Q9NZQ7 & P07766 & Q07011

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternate Names

GNC038, GNC-038, GNC038, 2559704-23-1

Background

Emfizatamab is an anti-CD19/CD3E/TNFRSF9/PD-L1 monoclonal antibody.

Note

For research use only. Not suitable for clinical or therapeutic use.

Images

SDS-PAGE

SDS-PAGE for Research Grade Emfizatamab.
Bioactivity

Detects recombinant CD137 (Catalog No: HC336011) in indirect ELISA.
Western blot

Western blot analysis was performed using anti-CD3E monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD3E (Catalog No: HY057021)

References

Datasheet

Anti-Human PD-L1&4-1BB/TNFRSF9/CD137&CD3&CD19 Multispecific Reference Antibody (Emfizatamab, RUO).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human PD-L1&4-1BB/TNFRSF9/CD137&CD3&CD19 Multispecific Reference Antibody (Emfizatamab, RUO) (HB996096)

Overview

Images

References

Datasheet

SDS

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