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Anti-Human Factor IXa & Factor X Bispecific Reference Antibody (Emicizumab, RUO) (HF610016)

Anti-Human Factor IXa & Factor X Bispecific Reference Antibody (Emicizumab, RUO)
Anti-Human Factor IXa & Factor X Bispecific Reference Antibody (Emicizumab, RUO)
Anti-Human Factor IXa & Factor X Bispecific Reference Antibody (Emicizumab, RUO)
Anti-Human Factor IXa & Factor X Bispecific Reference Antibody (Emicizumab, RUO)
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Overview
Catalog No.HF610016
Description
Emicizumab (HF610016) is a research-grade recombinant antibody targeting Stuart factor. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityHuman
ApplicationsELISA, Bioactivity: FCM, Functional assay, Research in vivo
Host speciesHuman
ClonalityMonoclonal
IsotypeIgG4-kappa
Clone IDEmicizumab
Expression system Mammalian cells
Nature Recombinant
Target Stuart factor, Stuart-Prower factor, Coagulation factor X, F10, Plasma thromboplastin component, F9, Christmas factor, Coagulation factor IX, PTC
Endotoxin level < 10 EU/mg as determined by LAL method.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession CAS: 1610943-06-0
Form Liquid
Storage buffer 0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesBispecific, ACE-910, RG6013, hBS910, 1610943-06-0
BackgroundDenecimig (Mim8) is a novel activated coagulation factor VIII-mimetic human bispecific antibody with anti-FIXa and anti-FX arms that potently stimulates FX activation resulting in efficacious haemostasis in vitro and in vivo.
Note For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)
Images
  • Anti-Human Factor IXa & Factor X Bispecific Reference Antibody (Emicizumab, RUO)

    Bioactivity

    SEC-HPLC detection for Research Grade Emicizumab.

  • Anti-Human Factor IXa & Factor X Bispecific Reference Antibody (Emicizumab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Emicizumab

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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