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Anti-Human TNF RII/TNFRSF1B Reference Antibody (Emunkitug, RUO) (HB070066)

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Anti-Human TNF RII/TNFRSF1B Reference Antibody (Emunkitug, RUO)

Anti-Human TNF RII/TNFRSF1B Reference Antibody (Emunkitug, RUO)

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Spec:

100ug
1mg

Number:

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Overview
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References
Datasheet
SDS

Overview

Catalog No.	HB070066
Description	emunkitug (HB070066) is a research-grade recombinant antibody targeting CD120. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG1, Kappa
Species	Human
Clonality	Monoclonal
Target	CD120b/TNFRSF1B/TNFR2
Purity	>95% as determined by SDS-PAGE.
Accession	P20333
Form	Liquid
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	2916519-48-5
Background	Tumor necrosis factor receptor superfamily member 1B (CD120b/TNFRSF1B) is a ~48 kDa protein. Receptor with high affinity for TNFSF2/TNF and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF. Isoform 2 blocks TNF-induced apoptosis, which suggests that it regulates TNF function by antagonizing its biological activity.
Note	For research use only. Not suitable for clinical or therapeutic use.

Images

SDS-PAGE

SDS-PAGE for Research Grade emunkitug

References

Datasheet

Anti-Human TNF RII/TNFRSF1B Reference Antibody (Emunkitug, RUO).pdf

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Formula

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Formula

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Stock Solution

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Working Solution

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Anti-Human TNF RII/TNFRSF1B Reference Antibody (Emunkitug, RUO)