Anti-Human MUC5AC Reference Antibody (Ensituximab, RUO) (HX246016)

Name: Anti-Human MUC5AC Reference Antibody (Ensituximab, RUO)
Brand: abinScience
SKU: HX246016
Price: 176 USD
Availability: InStock

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Overview

Catalog No.	HX246016
Description	Ensituximab (HX246016) is a research-grade recombinant antibody targeting Mucin-5 subtype AC. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Chimeric
Isotype	IgG1-kappa
Expression system	Mammalian cells
Clonality	Monoclonal
Target	Mucin-5 subtype AC, tracheobronchial, Gastric mucin, Mucin-5AC, TBM, MUC-5AC, Tracheobronchial mucin, Major airway glycoprotein, MUC5AC, MUC5
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P98088
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	NOE-102, NPC-1C, 1092658-06-4
Background	Mucin-5AC (MUC5AC) is a ~585 kDa protein. Gel-forming glycoprotein of gastric and respiratory tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microorganisms and particles that are subsequently removed by the mucociliary system. Interacts with H.pylori in the gastric epithelium, Barrett's esophagus as well as in gastric metaplasia of the duodenum (GMD). 1. Van de Bovenkamp, JH. et al. (2003) Helicobacter 8, 521-32. PMID: 14535999 2. Perez-Vilar, J. et al. (2004) Glycobiology 14, 325-37. PMID: 14718370
Note	For research use only. Not suitable for clinical or therapeutic use.