Anti-Human CD274/PD-L1/B7-H1 & CD152/CTLA4 Bispecific Reference Antibody (Erfonrilimab, RUO) (HV974146)

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100ug
1mg

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Overview

Catalog No.	HV974146
Description	Erfonrilimab (HV974146) is a research-grade recombinant antibody targeting CD152. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Humanized
Isotype	Single Domains (VH-VH'-CH), IgG1na;na
Expression system	Mammalian Cells
Clonality	Monoclonal
Target	CD152, Cytotoxic T-lymphocyte protein 4, CTLA-4, CTLA4, Cytotoxic T-lymphocyte-associated antigen 4, B7-H1, Programmed cell death 1 ligand 1, PDCD1 ligand 1, PDCD1L1, B7 homolog 1, PDCD1LG1, PDL1, hPD-L1, Programmed death ligand 1, B7H1, PD-L1, CD274
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P16410 & Q9NZQ7
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Bispecific, KN-046, KN046, 2367013-69-0
Background	Erfonrilimab (KN-046) is an anti-PDL1/CTLA-4 monoclonal antibody.
Note	For research use only. Not suitable for clinical or therapeutic use.

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Bioactivity

Detects CD274/PD-L1/B7-H1 in indirect ELISAs.

References

Datasheet

Anti-Human CD274/PD-L1/B7-H1 & CD152/CTLA4 Bispecific Reference Antibody (Erfonrilimab, RUO).pdf

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Recombinant Proteins

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Anti-Human CD274/PD-L1/B7-H1 & CD152/CTLA4 Bispecific Reference Antibody (Erfonrilimab, RUO) (HV974146)

Overview

Images

References

Datasheet

SDS

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