Anti-Human Tau Reference Antibody (Etalanetug, RUO) (HY086106)

Name: Anti-Human Tau Reference Antibody (Etalanetug, RUO)
Brand: abinScience
SKU: HY086106
Price: 176 USD
Availability: InStock

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Overview

Catalog No.	HY086106
Description	etalanetug (HY086106) is a research-grade recombinant antibody targeting MAPT/Tau/PHF-tau. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG1, Kappa
Species	Human
Clonality	Monoclonal
Target	MAPT/Tau/PHF-tau
Endotoxin level	< 10 EU/mg
Purity	>95% as determined by SDS-PAGE.
Accession	P10636
Form	Liquid
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	2690265-18-8
Background	Microtubule-associated protein tau (MAPT/PHF-tau) is a ~78 kDa protein. Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. 1. Yoshida, H. et al. (2012) Journal of neurochemistry 120, 165-76. PMID: 21985311 2. Sandberg, A. et al. (2020) Neurobiology of disease 146, 105079. PMID: 32961270
Note	For research use only. Not suitable for clinical or therapeutic use.

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Datasheet

Anti-Human Tau Reference Antibody (Etalanetug, RUO).pdf

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Anti-Human Tau Reference Antibody (Etalanetug, RUO) (HY086106)

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