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Anti-Human FGFR1&Klotho beta Bispecific Reference Antibody (Fazpilodemab, RUO) (HY105016)

Anti-Human FGFR1&Klotho beta Bispecific Reference Antibody (Fazpilodemab, RUO)
Anti-Human FGFR1&Klotho beta Bispecific Reference Antibody (Fazpilodemab, RUO)
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Overview
Catalog No.HY105016
Description
Fazpilodemab (HY105016) is a research-grade recombinant antibody targeting CD331. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHuman
IsotypeIgG1-kappa
Expression system Mammalian cells
Clonality Monoclonal
Target FLT2, HBGFR, BFGFR, FGFR-1, CEK, Fibroblast growth factor receptor 1, FGFR1, bFGF-R-1, Fms-like tyrosine kinase 2, FGFBR, FLT-2, CD331, Basic fibroblast growth factor receptor 1, FLG, Proto-oncogene c-Fgr, N-sam, Klotho beta-like protein, KLB, Beta-klotho, BetaKlotho, BKL
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P11362 & Q86Z14
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesBispecific, BFKB8488A, 2517935-02-1
BackgroundFazpilodemab (BFKB8488A) is a humanized, agonistic, bispecific antibody targeting fibroblast growth factor receptor 1c (FGFR1c) and Klothoβ. Fazpilodemab can be used for the research of type 2 diabetes mellitus (T2DM) or nonalcoholic fatty liver disease (NAFLD).
Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Human FGFR1&Klotho beta Bispecific Reference Antibody (Fazpilodemab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Fazpilodemab

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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