Anti-Human ErbB2/Her2 & PD-1 Bispecific Reference Antibody (Fidasimtamab, RUO) (HY286146)

Name: Anti-Human ErbB2/Her2 & PD-1 Bispecific Reference Antibody (Fidasimtamab, RUO)
Brand: abinScience
SKU: HY286146
Price: 220 USD
Availability: InStock

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Overview

Catalog No.	HY286146
Description	Fidasimtamab (HY286146) is a research-grade recombinant antibody targeting CD340. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG1-kappa
Expression system	Mammalian cells
Clonality	Monoclonal
Target	p185erbB2, HER2, NGL, Tyrosine kinase-type cell surface receptor HER2, NEU, MLN 19, Proto-oncogene Neu, MLN19, ERBB2, Proto-oncogene c-ErbB-2, CD340, Receptor tyrosine-protein kinase erbB-2, Metastatic lymph node gene 19 protein, Programmed cell death protein 1, Protein PD-1, hPD-1, PD1, PDCD1, CD279
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P04626 & Q15116
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Bispecific, BH-2950, BH2950, IBI315, IBI-315, IBI3152377419-89-9
Background	Fidasimtamab (IBI-315; BH2950) is a recombinant human IgG1 bispecific antibody that targets, binds and inhibits both HER2 and PD-1 and their downstream signalling pathways, and links PD-1 expressing T cells to HER2 expressing tumour cells. Fidasimtamab has potential immunosuppressive and antitumor activity.
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE for Research Grade Fidasimtamab

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Datasheet

Anti-Human ErbB2/Her2 & PD-1 Bispecific Reference Antibody (Fidasimtamab, RUO).pdf

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Anti-Human ErbB2/Her2 & PD-1 Bispecific Reference Antibody (Fidasimtamab, RUO) (HY286146)

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References

Datasheet

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