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Anti-Canine PD-1 Reference Antibody (Gilvetmab, RUO) (CS870016)

Anti-Canine PD-1 Reference Antibody (Gilvetmab, RUO)
Anti-Canine PD-1 Reference Antibody (Gilvetmab, RUO)
Anti-Canine PD-1 Reference Antibody (Gilvetmab, RUO)
Anti-Canine PD-1 Reference Antibody (Gilvetmab, RUO)
Anti-Canine PD-1 Reference Antibody (Gilvetmab, RUO)
Anti-Canine PD-1 Reference Antibody (Gilvetmab, RUO)
Anti-Canine PD-1 Reference Antibody (Gilvetmab, RUO)
Anti-Canine PD-1 Reference Antibody (Gilvetmab, RUO)
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  • Overview

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  • References

  • Datasheet

  • SDS

Overview
Catalog No.CS870016
Description
Gilvetmab (CS870016) is a research-grade recombinant antibody targeting CD279. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityCanine
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesCanine
IsotypeIgG2-kappa
Expression system Mammalian cells
Clonality Monoclonal
Target CD279/PDCD1/PD1
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession E2RPS2
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesAH-PD1, 1808081-43-7
BackgroundGilvetmab is a potent caninized anti-PD-1 monoclonal antibody. gilvetmab blocks the interaction between PD-1 and its ligand PDL-1.
• Diagnostic value of soluble programmed cell death protein-1 in type-1 autoimmune hepatitis in Egyptian children., PMID:31762332
Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Canine PD-1 Reference Antibody (Gilvetmab, RUO)

    Bioactivity

    Detects Dog CD279 in indirect ELISAs.

  • Anti-Canine PD-1 Reference Antibody (Gilvetmab, RUO)

    SEC-HPLC

    SEC-HPLC detection for Research Grade Gilvetmab.

  • Anti-Canine PD-1 Reference Antibody (Gilvetmab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Gilvetmab

  • Anti-Canine PD-1 Reference Antibody (Gilvetmab, RUO)

    Western blot

    Western blot analysis was performed using anti-dog PD1 monoclonal antibody at 1ug/mL on various samples.
    Lane 1: recombinant Dog CD279/PDCD1/PD1 (Catalog No: CS870011)
    Lane 2: negative control

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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