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Anti-HRSV Fusion Glycoprotein Reference Antibody (Gontivimab, RUO) (VK421066)

Anti-HRSV Fusion Glycoprotein Reference Antibody (Gontivimab, RUO)
Anti-HRSV Fusion Glycoprotein Reference Antibody (Gontivimab, RUO)
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  • Datasheet

  • SDS

Overview
Catalog No.VK421066
Description
Gontivimab (VK421066) is a research-grade recombinant antibody targeting F. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityHuman respiratory syncytial virus A (HRSV-A)
ApplicationsELISA, Bioactivity: FCM, Functional assay, Research in vivo
Host speciesAlpaca
ClonalityMonoclonal
IsotypeVH-VH-VH
Target F, F1, F2, Fusion glycoprotein F0, Fusion glycoprotein F1, Fusion glycoprotein F2, Intervening segment, Pep27, Peptide 27, p27
Endotoxin level < 10 EU/mg
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P03420, P11209, 12568, O36634, P13843
Form Liquid
Storage buffer 0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesALX-0171, VR-465, 1257358-38-5
Background

Fusion glycoprotein F0 is a ~63 kDa protein. Inactive precursor that is cleaved at two sites by a furin-like protease to give rise to the mature F1 and F2 fusion glycoproteins.

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-HRSV Fusion Glycoprotein Reference Antibody (Gontivimab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Gontivimab

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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