Anti-Human Claudin-18.2 & CD3 epsilon Bispecific Reference Antibody (Gresonitamab, RUO) (HX126026)

Name: Anti-Human Claudin-18.2 & CD3 epsilon Bispecific Reference Antibody (Gresonitamab, RUO)
Brand: abinScience
SKU: HX126026
Price: 220 USD
Availability: InStock

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References
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SDS

Overview

Catalog No.	HX126026
Description	Gresonitamab (HX126026) is a research-grade recombinant antibody targeting CD3. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Host species	Human
Clonality	Monoclonal
Isotype	(scFv-heavy-kappa)-(scFv-heavy-lambda)-scFc
Tested applications	FCM
Target	CLDN18.2, Claudin-18.2, CD3E, CD3e, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, T3E
Endotoxin level	< 10 EU/mg
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P56856-2 & P07766
Form	Liquid
Storage buffer	0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Bispecific, AMG910, AMG-910, AMG9102413817-97-5
Background	Gresonitamab (AMG 910) is a half-life extended (HLE) bispecific T-cell engager (BiTE) antibody targets CD3-positive T cells and CLDN18.2-expressing tumor cells. Gresonitamab can be used for the research of adenocarcinoma.
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

Images

SDS-PAGE

SDS-PAGE for Research Grade Gresonitamab
Flow cytometry

Flow-cytometry APC using anti-human CLDN18.2 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an APC anti-human CLDN18.2 monoclonal antibody (Catalog HX126026) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

References

Datasheet

Anti-Human Claudin-18.2 & CD3 epsilon Bispecific Reference Antibody (Gresonitamab, RUO).pdf

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Recombinant Proteins

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Anti-Human Claudin-18.2 & CD3 epsilon Bispecific Reference Antibody (Gresonitamab, RUO) (HX126026)

Overview

Images

References

Datasheet

SDS

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