Anti-Human CLDN18.2 & CD3 epsilon Bispecific Reference Antibody (Gresonitamab, RUO) (HX126026)

Name: Anti-Human CLDN18.2 & CD3 epsilon Bispecific Reference Antibody (Gresonitamab, RUO)
Brand: abinScience
SKU: HX126026
Price: 220 USD
Availability: InStock

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SDS

Overview

Catalog No.	HX126026
Description	Gresonitamab (HX126026) is a research-grade recombinant antibody targeting CD3. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	(scFv-heavy-kappa)-(scFv-heavy-lambda)-scFc
Expression system	Mammalian cells
Clonality	Monoclonal
Target	Claudin-18, CLDN18, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P56856-2 & P07766
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Bispecific, AMG910, AMG-910, AMG9102413817-97-5
Background	Gresonitamab (AMG 910) is a half-life extended (HLE) bispecific T-cell engager (BiTE) antibody targets CD3-positive T cells and CLDN18.2-expressing tumor cells. Gresonitamab can be used for the research of adenocarcinoma.
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade Gresonitamab
Flow cytometry

Flow-cytometry APC using anti-human CLDN18.2 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an APC anti-human CLDN18.2 monoclonal antibody (Catalog HX126026) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

References

Datasheet

Anti-Human CLDN18.2 & CD3 epsilon Bispecific Reference Antibody (Gresonitamab, RUO).pdf

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Recombinant Proteins

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Anti-Human CLDN18.2 & CD3 epsilon Bispecific Reference Antibody (Gresonitamab, RUO) (HX126026)

Overview

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References

Datasheet

SDS

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