Anti-Human VEGFR2/KDR/Flk-1 Reference Antibody (Inlecitug, RUO) (HW338126)

Name: Anti-Human VEGFR2/KDR/Flk-1 Reference Antibody (Inlecitug, RUO)
Brand: abinScience
SKU: HW338126
Price: 192 USD
Availability: InStock

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Overview

Catalog No.	HW338126
Description	inlecitug (HW338126) is a research-grade recombinant antibody targeting CD309. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research.
Species reactivity	Human
Applications	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Host species	Human
Clonality	Monoclonal
Isotype	IgG1, Kappa
Target	CD309, EC:2.7.10.1, FLK-1, FLK1, Fetal liver kinase 1, KDR, Kinase insert domain receptor, Protein-tyrosine kinase receptor flk-1, VEGFR-2, VEGFR2, Vascular endothelial growth factor receptor 2
Endotoxin level	< 10 EU/mg
Purity	>95% as determined by SDS-PAGE.
Accession	P35968
Form	Liquid
Storage buffer	0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	2997627-68-4
Background	Vascular endothelial growth factor receptor 2 (CD309/KDR) is a ~151 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain, such as isoform 2 and isoform 3, may function as decoy receptors for VEGFA, VEGFC and/or VEGFD.
Note	For research use only. Not suitable for clinical or therapeutic use.