Anti-Human ADAMTS5 & ALB Bispecific Reference Antibody (Isecarosmab, RUO) (HP572016)

Name: Anti-Human ADAMTS5 & ALB Bispecific Reference Antibody (Isecarosmab, RUO)
Brand: abinScience
SKU: HP572016
Price: 220 USD
Availability: InStock

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Overview

Catalog No.	HP572016
Description	Isecarosmab (HP572016) is a research-grade recombinant antibody targeting A disintegrin and metalloproteinase with thrombospondin m.... Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Host species	Humanized(Lama/glama)
Clonality	Monoclonal
Isotype	VH-VH'
Clone ID	Isecarosmab
Expression system	Mammalian cells
Nature	Recombinant
Target	A disintegrin and metalloproteinase with thrombospondin motifs 5, ADAM-TS 5, ADAM-TS5, ADAMTS-5, EC:3.4.24.-, A disintegrin and metalloproteinase with thrombospondin motifs 11, ADAM-TS 11, ADAMTS-11, ADMP-2, Aggrecanase-2, ADAMTS5, ALB, Albumin
Endotoxin level	< 10 EU/mg as determined by LAL method.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q9UNA0 & P02768
Form	Liquid
Storage buffer	0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Bispecific, M-6495, 2254082-79-4
Background	Isecarosmab (M-6495) is an anti-ADAMTS monoclonal antibody (mAb) with a KD value of 3.65 pM. Isecarosmab has chondroprotective and anti-inflammatory activities. Isecarosmab can bind albumin to extend plasma half-life.
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade Isecarosmab.

References

Datasheet

Anti-Human ADAMTS5 & ALB Bispecific Reference Antibody (Isecarosmab, RUO).pdf

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Formula

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Recombinant Proteins

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Anti-Human ADAMTS5 & ALB Bispecific Reference Antibody (Isecarosmab, RUO) (HP572016)

Overview

Images

References

Datasheet

SDS