Anti-Human PD-1&IL-21R Reference Antibody (Latikafusp, RUO) (HV076016)

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100ug
1mg

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Overview

Catalog No.	HV076016
Description	Latikafusp (HV076016) is a research-grade recombinant antibody targeting CD360. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG1-lambda2
Expression system	Mammalian Cells
Clonality	Monoclonal
Target	IL21R, NILR, Interleukin-21 receptor, IL-21R, IL-21 receptor, CD360, Novel interleukin receptor, Programmed cell death protein 1, Protein PD-1, hPD-1, PD1, PDCD1, CD279
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q9HBE5 & Q15116
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Bispecificantibody, AMG256, AMG-256, AMG256, 2552814-07-8
Background	Latikafusp (AMG 256) is a bifunctional fusion protein comprising a PD-1-targeting antibody and IL-21 mutein designed to deliver IL-21 pathway stimulation to PD-1+ cells. Latikafusp is designed to prime and extend the activity of cytotoxic and memory T cells and induce anti-tumor immunity. Latikafusp has the potential for solid tumors research.Latikafusp may lead to the development of immunogenicity-mediated responses.
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE for Research Grade Latikafusp

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Datasheet

Anti-Human PD-1&IL-21R Reference Antibody (Latikafusp, RUO).pdf

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Anti-Human PD-1&IL-21R Reference Antibody (Latikafusp, RUO) (HV076016)

Overview

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References

Datasheet

SDS

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