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Research Grade lenipagrusin alfa (PR006016)

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Overview
Catalog No.PR006016
Description
lenipagrusin alfa (PR006016) is a research-grade recombinant antibody targeting Seed leukoagglutinin / MALS.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
Species reactivityMaackia amurensis
ApplicationsFunctional assay
IsotypeSeed leukoagglutinin / MALS
Target Seed leukoagglutinin / MALS
Endotoxin level < 10 EU/mg
Purity >95% as determined by SDS-PAGE
Accession P0DKL3
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesCAS: 3038720-27-0
Background

Seed leukoagglutinin is a ~31 kDa protein. Sialic acid-binding lectin recognizing oligosaccharides containing terminal sialic acid linked via alpha-2,3 bond to penultimate galactose residues. Binds the trisaccharide sequence Neu5Ac-alpha-2,3-Gal-beta-1,4-GlcNAc. Binds fetuin when fully glycosylated but not when the high mannose-type glycans are removed, although the secondary structure is virtually unaffected by deglycosylation of the high mannose-type glycans. The lectin activity may depend on the presence of a single GlcNAc attached to N-90.

1. Wang, WC. et al. (1988) The Journal of biological chemistry 263, 4576-85. PMID: 3350806
2. Knibbs, RN. et al. (1991) The Journal of biological chemistry 266, 83-8. PMID: 1985926
3. Kim, BS. et al. (2015) Biochimica et biophysica acta 1850, 1815-21. PMID: 26003537
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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