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Anti-Human KIR2DL1/CD158a&KIR2DL2/CD158b1&KIR2DL3/CD158b2&KIR2DS1/CD158h&KIR2DS2 Reference Antibody (Lirilumab, RUO) (HW759016)

Anti-Human KIR2DL1/CD158a&KIR2DL2/CD158b1&KIR2DL3/CD158b2&KIR2DS1/CD158h&KIR2DS2 Reference Antibody (Lirilumab, RUO)
Anti-Human KIR2DL1/CD158a&KIR2DL2/CD158b1&KIR2DL3/CD158b2&KIR2DS1/CD158h&KIR2DS2 Reference Antibody (Lirilumab, RUO)
Anti-Human KIR2DL1/CD158a&KIR2DL2/CD158b1&KIR2DL3/CD158b2&KIR2DS1/CD158h&KIR2DS2 Reference Antibody (Lirilumab, RUO)
Anti-Human KIR2DL1/CD158a&KIR2DL2/CD158b1&KIR2DL3/CD158b2&KIR2DS1/CD158h&KIR2DS2 Reference Antibody (Lirilumab, RUO)
Anti-Human KIR2DL1/CD158a&KIR2DL2/CD158b1&KIR2DL3/CD158b2&KIR2DS1/CD158h&KIR2DS2 Reference Antibody (Lirilumab, RUO)
Anti-Human KIR2DL1/CD158a&KIR2DL2/CD158b1&KIR2DL3/CD158b2&KIR2DS1/CD158h&KIR2DS2 Reference Antibody (Lirilumab, RUO)
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Overview
Catalog No.HW759016
Description
Lirilumab (HW759016) is a research-grade recombinant antibody targeting CD158. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHuman
IsotypeIgG4-kappa
Expression system Mammalian cells
Clonality Monoclonal
Target CD158 antigen-like family member A, KIR2DL1, Killer cell immunoglobulin-like receptor 2DL1, Natural killer-associated transcript 1, NKAT-1, MHC class I NK cell receptor, CD158A, p58 natural killer cell receptor clones CL-42/47.11, CD158a, p58.1 MHC class-I-specific NK receptor, NKAT1, p58 NK receptor CL-42/47.11, p58 NK receptor CL-43, NKAT-6, NKAT6, MHC class I NK cell receptor, CD158 antigen-like family member B1, CD158b1, p58 natural killer cell receptor clone CL-43, Natural killer-associated transcript 6, CD158B1, KIR2DL2, Killer cell immunoglobulin-like receptor 2DL2, NKAT2b, KIR2DL3, p58 natural killer cell receptor clone CL-6, p58.2 MHC class-I-specific NK receptor, CD158 antigen-like family member B2, MHC class I NK cell receptor, KIR-023GB, Killer inhibitory receptor cl 2-3, p58 NK receptor CL-6, CD158b2, Killer cell immunoglobulin-like receptor 2DL3, Natural killer-associated transcript 2, CD158B2, KIRCL23, NKAT-2, NKAT2a, NKAT2
Endotoxin level < 10 EU/mg
Purity >95% purity by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P43626 & P43627 & P43628
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesBMS-986015, IPH2102, 1000676-41-4
BackgroundLirilumab (IPH2102) is an anti-KIR monoclonal antibody, and shows antitumor activity. Lirilumab can be used in Leukemia, squamous cell carcinoma of the head and neck (SCCHN) research.
Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Human KIR2DL1/CD158a&KIR2DL2/CD158b1&KIR2DL3/CD158b2&KIR2DS1/CD158h&KIR2DS2 Reference Antibody (Lirilumab, RUO)

    SEC-HPLC

    SEC-HPLC detection for Research Grade Lirilumab.

  • Anti-Human KIR2DL1/CD158a&KIR2DL2/CD158b1&KIR2DL3/CD158b2&KIR2DS1/CD158h&KIR2DS2 Reference Antibody (Lirilumab, RUO)

    Bioactivity

    Detects Human CD158b1/KIR2DL2 in indirect ELISAs.

  • Anti-Human KIR2DL1/CD158a&KIR2DL2/CD158b1&KIR2DL3/CD158b2&KIR2DS1/CD158h&KIR2DS2 Reference Antibody (Lirilumab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Lirilumab.

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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