Anti-Human GM-CSF R alpha Reference Antibody (Mavrilimumab, RUO) (HB112016)

Name: Anti-Human GM-CSF R alpha Reference Antibody (Mavrilimumab, RUO)
Brand: abinScience
SKU: HB112016
Price: 176 USD
Availability: InStock

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Overview

Catalog No.	HB112016
Description	Mavrilimumab (HB112016) is a research-grade recombinant antibody targeting CD116. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG4-lambda2
Expression system	Mammalian cells
Clonality	Monoclonal
Target	CD116, CSF2R, GMR-alpha, CSF2RA, Granulocyte-macrophage colony-stimulating factor receptor subunit alpha, CSF2RY, GMCSFR-alpha, GM-CSF-R-alpha, CDw116
Endotoxin level	< 10 EU/mg
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P15509
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CAM-3001, 1085337-57-0
Background	Granulocyte-macrophage colony-stimulating factor receptor subunit alpha (CD116/CSF2RA) is a ~46 kDa protein. Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells.
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207) Human IgG4 (S228P & L235E) Recombinant Isotype Control Antibody (HyHEL-10) (HP614107) Human IgG4 (S228P) Recombinant Isotype Control Antibody (SAA0184) (HP298107)

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Bioactivity

Detects CD116/CSF2RA in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Anti-Human GM-CSF R alpha Reference Antibody (Mavrilimumab, RUO)

References

Datasheet

Anti-Human GM-CSF R alpha Reference Antibody (Mavrilimumab, RUO).pdf

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Anti-Human GM-CSF R alpha Reference Antibody (Mavrilimumab, RUO) (HB112016)

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