Anti-Human GM-CSF R alpha Reference Antibody (Mavrilimumab, RUO) (HB112016)

Name: Anti-Human GM-CSF R alpha Reference Antibody (Mavrilimumab, RUO)
Brand: abinScience
SKU: HB112016
Price: 176 USD
Availability: InStock

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Overview

Catalog No.	HB112016
Description	Mavrilimumab (HB112016) is a research-grade recombinant antibody targeting CD116. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG4-lambda2
Expression system	Mammalian cells
Clonality	Monoclonal
Target	CD116, CSF2R, GMR-alpha, CSF2RA, Granulocyte-macrophage colony-stimulating factor receptor subunit alpha, CSF2RY, GMCSFR-alpha, GM-CSF-R-alpha, CDw116
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P15509
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CAM-3001, 1085337-57-0
Background	Granulocyte-macrophage colony-stimulating factor receptor subunit alpha (CD116/CSF2RA) is a ~46 kDa protein. Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells.
Note	For research use only. Not suitable for clinical or therapeutic use.

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Bioactivity

Detects CD116/CSF2RA in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Anti-Human GM-CSF R alpha Reference Antibody (Mavrilimumab, RUO)

References

Datasheet

Anti-Human GM-CSF R alpha Reference Antibody (Mavrilimumab, RUO).pdf

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Anti-Human GM-CSF R alpha Reference Antibody (Mavrilimumab, RUO) (HB112016)

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Datasheet

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