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Anti-Human 5'-Nucleotidase/CD73 Reference Antibody (Mavrostobart, RUO) (HB209166)

Anti-Human 5'-Nucleotidase/CD73 Reference Antibody (Mavrostobart, RUO)
Anti-Human 5'-Nucleotidase/CD73 Reference Antibody (Mavrostobart, RUO)
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Overview
Catalog No.HB209166
Description
mavrostobart (HB209166) is a research-grade recombinant antibody targeting CD73.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
Species reactivityHuman
ApplicationsELISA, Bioactivity: FCM, Functional assay, Research in vivo
Host speciesHuman
ClonalityMonoclonal
IsotypeIgG4, Kappa
Expression system Mammalian cells
Nature Recombinant
Target 5'-NT, 5'-deoxynucleotidase, 5'-nucleotidase, CD73, EC:3.1.3.35, EC:3.1.3.5, EC:3.1.3.89, EC:3.1.3.91, EC:3.1.3.99, Ecto-5'-nucleotidase, IMP-specific 5'-nucleotidase, NT5, NT5E, NTE, Thymidylate 5'-phosphatase
Endotoxin level < 10 EU/mg as determined by LAL method.
Purity >95% as determined by SDS-PAGE.
Accession P21589
Form Liquid
Storage buffer 0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Shipping In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names2928515-12-0
Background

5'-nucleotidase (CD73/NT5E) is a ~63 kDa protein. Catalyzes the hydrolysis of nucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside. Hydrolyzes IMP. Shows a preference for ribonucleotide monophosphates over their equivalent deoxyribose forms. Although AMP is the preferred substrate can also hydrolyze UMP, GMP, CMP, dAMP, dCMP, dTMP, NAD and NMN.

1. Resta, R. et al. (1993) Gene 133, 171-7. PMID: 8224905
Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Human 5'-Nucleotidase/CD73 Reference Antibody (Mavrostobart, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade mavrostobart

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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