Anti-Human KLB/Beta-klotho Reference Antibody (Mk-3655, RUO) (HV266016)

Name: Anti-Human KLB/Beta-klotho Reference Antibody (Mk-3655, RUO)
Brand: abinScience
SKU: HV266016
Price: 176 USD
Availability: InStock

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Overview

Catalog No.	HV266016
Description	MK-3655 (HV266016) is a research-grade recombinant antibody targeting Klotho beta-like protein. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG1-kappa
Expression system	Mammalian cells
Clonality	Monoclonal
Target	Klotho beta-like protein, KLB, Beta-klotho, BetaKlotho, BKL
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q86Z14
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	MK-3655, NGM-313, NGM313
Background	Beta-klotho (KLB) is a ~119 kDa protein. Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21.
Note	For research use only. Not suitable for clinical or therapeutic use.