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Anti-Human HLA-G & CD3 epsilon Bispecific Reference Antibody (Obertamig, RUO) (HM815036)

Anti-Human HLA-G & CD3 epsilon Bispecific Reference Antibody (Obertamig, RUO)
Anti-Human HLA-G & CD3 epsilon Bispecific Reference Antibody (Obertamig, RUO)
Anti-Human HLA-G & CD3 epsilon Bispecific Reference Antibody (Obertamig, RUO)
Anti-Human HLA-G & CD3 epsilon Bispecific Reference Antibody (Obertamig, RUO)
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  • Overview

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  • Datasheet

  • SDS

Overview
Catalog No.HM815036
Description
Obertamig (HM815036) is a research-grade recombinant antibody targeting CD3. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo, WB
Host speciesHuman
Isotypehalf IG G1-lambda2/scFv-h-CH2-CH3
Expression system Mammalian cells
Clonality Monoclonal
Tested applications WB
Target HLAG, HLA-G, sHLA-G, HLA G antigen, MHC class I antigen G, HLA-6.0, HLA class I histocompatibility antigen, alpha chain G, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
Endotoxin level < 10 EU/mg
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P17693 & P07766
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names2750126-32-8
BackgroundObertamig is an engineered, humanized, anti-CD3E/HLA-G monoclonal antibody with humanized CH2-CH3 modifications and consists of half immunoglobulin IgG1 λ2 and a single-chain variable fragment (scFv).
Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Human HLA-G & CD3 epsilon Bispecific Reference Antibody (Obertamig, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Obertamig

  • Anti-Human HLA-G & CD3 epsilon Bispecific Reference Antibody (Obertamig, RUO)

    Western blot

    Western blot analysis was performed using anti-CD3E monoclonal antibody at 1ug/mL on various samples.
    Lane 1: recombinant human CD3E (Catalog No: HY057021)
    Lane 2: Negative control

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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