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Anti-Human EDNRA/Endothelin R Type A Reference Antibody (Patecibart, RUO) (HB817016)

Anti-Human EDNRA/Endothelin R Type A Reference Antibody (Patecibart, RUO)
Anti-Human EDNRA/Endothelin R Type A Reference Antibody (Patecibart, RUO)
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Overview
Catalog No.HB817016
Description
Patecibart (HB817016) is a research-grade recombinant antibody targeting Endothelin-1 receptor. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHuman
IsotypeIgG4-kappa
Expression system Mammalian cells
Clonality Monoclonal
Target Endothelin-1 receptor, ETA, ET-A, ETRA, Endothelin receptor type A, EDNRA, hET-AR, ETA-R
Endotoxin level Please contact the lab for this information.
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P25101
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names2642374-04-5
Background

Endothelin-1 receptor (EDNRA/ETA) is a ~48 kDa protein. Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Human EDNRA/Endothelin R Type A Reference Antibody (Patecibart, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Patecibart.

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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