Anti-Human LIGHT/TNFSF14 Reference Antibody (Quisovalimab, RUO) (HT145016)

Name: Anti-Human LIGHT/TNFSF14 Reference Antibody (Quisovalimab, RUO)
Brand: abinScience
SKU: HT145016
Price: 176 USD
Availability: InStock

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Overview

Catalog No.	HT145016
Description	Quisovalimab (HT145016) is a research-grade recombinant antibody targeting CD258. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG4-kappa
Expression system	Mammalian cells
Clonality	Monoclonal
Target	Herpes virus entry mediator ligand, LIGHT, CD258, HVEM-L, HVEML, TNFSF14, Tumor necrosis factor ligand superfamily member 14, Herpesvirus entry mediator ligand
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	O43557
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	AEVI-002, CERC-002, F-19, MDGN-002, SAR-2520672427667-03-4
Background	Tumor necrosis factor ligand superfamily member 14 (CD258/TNFSF14) is a ~26 kDa protein. Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Acts as a ligand for TNFRSF14/HVEM. Upon binding to TNFRSF14/HVEM, delivers costimulatory signals to T cells, leading to T cell proliferation and IFNG production. 1. Tamada, K. et al. (2000) Journal of immunology (Baltimore, Md. : 1950) 164, 4105-10. PMID: 10754304 2. Mauri, DN. et al. (1998) Immunity 8, 21-30. PMID: 9462508
Note	For research use only. Not suitable for clinical or therapeutic use.

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SEC-HPLC

SEC-HPLC detection for Research Grade Quisovalimab.
SDS-PAGE

SDS-PAGE for Research Grade Quisovalimab.

References

Datasheet

Anti-Human LIGHT/TNFSF14 Reference Antibody (Quisovalimab, RUO).pdf

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Anti-Human LIGHT/TNFSF14 Reference Antibody (Quisovalimab, RUO) (HT145016)

Overview

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References

Datasheet

SDS

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