Anti-RABV glycoprotein G Reference Antibody (Rafivirumab, RUO) (VK632066)

Name: Anti-RABV glycoprotein G Reference Antibody (Rafivirumab, RUO)
Brand: abinScience
SKU: VK632066
Price: 176 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.	VK632066
Description	Research Grade Rafivirumab (VK632066) is a canis monoclonal antibody detecting Glycoprotein in ELISA, FACS, Functional assay, Research in vivo. Suitable for Rabies virus (RABV). Highlights ●Multi-Application — Validated across multiple applications.
Species reactivity	Rabies virus (RABV)
Applications	ELISA, FACS, Functional assay, Research in vivo
Host species	Canine
Isotype	IgG2a, kappa
Clonality	Monoclonal
Tested applications	WB
Target	Glycoprotein, G
Endotoxin level	< 10 EU/mg
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	O92284
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Glycoprotein (glycoprotein G) is a ~58 kDa protein. Attaches the virus to host cellular receptor, inducing endocytosis of the virion by using different host proteins including TFRC, GRM2 and ITGB1. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.
Note	For research use only.

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SDS-PAGE

SDS-PAGE for Research Grade Rafivirumab
Western blot

Western blot analysis was performed using anti-/ monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant Rabies virus/RABV G/Glycoprotein(Catalog No: VK632012)
Lane 2: negative control