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Anti-Human TNFA & IL17A Bispecific Reference Antibody (Remtolumab, RUO) (HS856096)

Anti-Human TNFA & IL17A Bispecific Reference Antibody (Remtolumab, RUO)
Anti-Human TNFA & IL17A Bispecific Reference Antibody (Remtolumab, RUO)
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Overview
Catalog No.HS856096
Description
Research Grade Remtolumab (HS856096) is a human monoclonal antibody detecting CTLA-8 in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human.
Highlights
  • Multi-Application — Validated across multiple applications.
Species reactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHuman
Isotype[VH-VH'-H-Gamma1-VL-VL'-C-kappa]-dimer
Expression system Mammalian cells
Species Human
Clonality Monoclonal
Target CTLA-8, Cytotoxic T-lymphocyte-associated antigen 8, IL17, IL-17A, IL17A, CTLA8, IL-17, Interleukin-17A, TNF, Tumor necrosis factor ligand superfamily member 2, N-terminal fragment, ICD2, NTF, TNF-a, TNF-alpha, Tumor necrosis factor, TNFSF2, TNFA, Cachectin, ICD1
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q16552 & P01375
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesBispecific, A-1230717, ABT-122, 1791410-27-9
BackgroundRemtolumab (ABT-122) is a dual-variable domain immunoglobulin that neutralises both tumor necrosis factor α (TNFα) and IL-17A. Remtolumab shows dual inhibition of TNFα and IL-17A. Remtolumab can be used for rheumatoid arthritis (RA) research.
Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Human TNFA & IL17A Bispecific Reference Antibody (Remtolumab, RUO)

    Bioactivity

    Detects IL17A in indirect ELISAs.

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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