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Research Grade rugecitide (HV222016)

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Overview
Catalog No.HV222016
Description
rugecitide (HV222016) is a research-grade recombinant antibody targeting neuregulina 4/NRG4.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
Species reactivityHuman
ApplicationsELISA, Functional assay, Research in vivo
Species Human
Target neuregulina 4/NRG4
Purity >95% as determined by SDS-PAGE.
Accession Q8WWG1
Form Liquid
Reconstitution Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names2938226-27-6
Background

Pro-neuregulin-4, membrane-bound isoform (neuregulina 4/NRG4) is a ~12 kDa protein. Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors.

Note For research use only. Not suitable for clinical or therapeutic use.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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