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Anti-Human IL-17A/F Heterodimer & ALB Multispecific Reference Antibody (Sonelokimab, RUO) (HS856086)

Anti-Human IL-17A/F Heterodimer & ALB Multispecific Reference Antibody (Sonelokimab, RUO)
Anti-Human IL-17A/F Heterodimer & ALB Multispecific Reference Antibody (Sonelokimab, RUO)
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Overview
Catalog No.HS856086
Description
Sonelokimab (HS856086) is a research-grade recombinant antibody targeting CTLA-8. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHuman
IsotypeVH-VH'-VH
Expression system Mammalian cells
Clonality Monoclonal
Target CTLA-8, Cytotoxic T-lymphocyte-associated antigen 8, IL17, IL-17A, IL17A, CTLA8, IL-17, Interleukin-17A, IL17F, Interleukin-17F, IL-17F, Cytokine ML-1, ALB, Albumin
Endotoxin level < 10 EU/mg
Purity >95% purity as determined by SDS-PAGE.
Purification Purified by Nickel column.
Accession Q16552 & Q96PD4 & P02768
Form Liquid
Storage buffer 30 mM Histidine, pH5.8, 10% sucrose, 0.02% Tween80

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesBispecific, Trivalent, M-1095, MSB-0010841, 1414386-05-2
BackgroundSonelokimab (ALX 0761) is a trivalent bispecific nanobody composed of camel derived humanized IL-17F antibodies, IL-17A/F antibodies, and serum albumin VHH antibodies. Sonelokimab can prolong the plasma half-life by binding to human serum albumin. Sonelokimab can be used for research on rheumatoid arthritis and psoriasis.
Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Human IL-17A/F Heterodimer & ALB Multispecific Reference Antibody (Sonelokimab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Sonelokimab

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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