Anti-HIV-1 gp120 Reference Antibody (Suvizumab, RUO) (VK617016)

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100ug
1mg

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Overview

Catalog No.	VK617016
Description	Suvizumab (VK617016) is a research-grade recombinant antibody targeting env/Env polyprotein. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human immunodeficiency virus 1 (HIV-1)
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Humanized
Isotype	IgG1, kappa
Expression system	Mammalian Cells
Clonality	Monoclonal
Target	env/Env polyprotein
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P03377
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names	KD-247, 914257-21-9
Background	Envelope glycoprotein gp160 (Envpolyprotein) is a ~97 kDa protein. Oligomerizes in the host endoplasmic reticulum into predominantly trimers. In a second time, gp160 transits in the host Golgi, where glycosylation is completed. The precursor is then proteolytically cleaved in the trans-Golgi and thereby activated by cellular furin or furin-like proteases to produce gp120 and gp41.
Note	For research use only. Not suitable for clinical or therapeutic use.

Images

SEC-HPLC

SEC-HPLC detection for Research Grade Suvizumab.
Bioactivity

Detects env/Env polyprotein in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Suvizumab.

References

Datasheet

Anti-HIV-1 gp120 Reference Antibody (Suvizumab, RUO).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

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Anti-HIV-1 gp120 Reference Antibody (Suvizumab, RUO) (VK617016)

Overview

Images

References

Datasheet

SDS

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