Anti-Human B7-H3 Reference Antibody (Tambotatug, RUO) (HV612106)

Name: Anti-Human B7-H3 Reference Antibody (Tambotatug, RUO)
Brand: abinScience
SKU: HV612106
Price: 370 USD
Availability: InStock

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Overview

Catalog No.	HV612106
Description	tambotatug (HV612106) is a research-grade recombinant antibody targeting CD276. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research.
Species reactivity	Human
Applications	ELISA, FACS, Functional assay
Host species	Human
Isotype	IgG1, kappa
Target	CD276/B7-H3
Purity	>95% as determined by SDS-PAGE
Accession	Q5ZPR3
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CAS: 2925042-44-8
Background	CD276 antigen is a ~57 kDa protein. May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses.
Note	For research use only.