Anti-Human Notch-2/Notch-3 Reference Antibody (Tarextumab, RUO) (HC513016)

Name: Anti-Human Notch-2/Notch-3 Reference Antibody (Tarextumab, RUO)
Brand: abinScience
SKU: HC513016
Price: 176 USD
Availability: InStock

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Overview

Catalog No.	HC513016
Description	Tarextumab (HC513016) is a research-grade recombinant antibody targeting N2ICD. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG2-kappa
Expression system	Mammalian cells
Clonality	Monoclonal
Target	N2ICD, N2ECD, NOTCH2, hN2, Neurogenic locus notch homolog protein 2, Notch 2, Neurogenic locus notch homolog protein 3, NOTCH3, Notch 3
Endotoxin level	< 10 EU/mg
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q04721 & Q9UM47
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	OMP-59R5, 1359940-55-8
Background	Tarextumab (OMP-59R5) is an anti-Notch2/3 fully human IgG2 monoclonal antibody. Tarextumab shows anti-tumor activity.
Note	For research use only. Not suitable for clinical or therapeutic use.

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Bioactivity

Detects NOTCH2 in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Tarextumab.

References

Datasheet

Anti-Human Notch-2/Notch-3 Reference Antibody (Tarextumab, RUO).pdf

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Recombinant Proteins

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Anti-Human Notch-2/Notch-3 Reference Antibody (Tarextumab, RUO) (HC513016)

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References

Datasheet

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