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Anti-Human IL-17A & TNFSF13B Bispecific Reference Antibody (Tibulizumab, RUO) (HS856106)

Anti-Human IL-17A & TNFSF13B Bispecific Reference Antibody (Tibulizumab, RUO)
Anti-Human IL-17A & TNFSF13B Bispecific Reference Antibody (Tibulizumab, RUO)
Anti-Human IL-17A & TNFSF13B Bispecific Reference Antibody (Tibulizumab, RUO)
Anti-Human IL-17A & TNFSF13B Bispecific Reference Antibody (Tibulizumab, RUO)
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Overview
Catalog No.HS856106
Description
Research Grade Tibulizumab (HS856106) is a humanized monoclonal antibody detecting CTLA-8 in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human.
Highlights
  • ●Multi-Application — Validated across multiple applications.
Species reactivityHuman
ApplicationsELISA, Bioactivity: FCM, Functional assay, Research in vivo
Host speciesHuman
ClonalityMonoclonal
IsotypeIgG4-kappa-[scFv]2
Clone IDTibulizumab
Expression system Mammalian cells
Nature Recombinant
Target CTLA-8, CTLA8, Cytotoxic T-lymphocyte-associated antigen 8, IL-17, IL-17A, IL17, IL17A, Interleukin-17A, B lymphocyte stimulator, B-cell-activating factor, BAFF, BLYS, BLyS, CD257, Dendritic cell-derived TNF-like molecule, TALL-1, TALL1, TNF- and APOL-related leukocyte expressed ligand 1, TNFSF13B, TNFSF20, Tumor necrosis factor ligand superfamily member 13B, Tumor necrosis factor ligand superfamily member 13b, membrane form, Tumor necrosis factor ligand superfamily member 13b, soluble form, ZTNF4
Endotoxin level < 10 EU/mg as determined by LAL method.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q16552 & Q9Y275
Form Liquid
Storage buffer 0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesBispecific, LY 3090106, LY-3090106, LY3090106, 1849636-24-3
BackgroundTibulizumab (LY-3090106) is a tetravalent bispecific antibody targeting BAFF and IL-17A for the treatment of autoimmune disease.
Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Human IL-17A & TNFSF13B Bispecific Reference Antibody (Tibulizumab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Tibulizumab.

  • Anti-Human IL-17A & TNFSF13B Bispecific Reference Antibody (Tibulizumab, RUO)

    Bioactivity

    Detects Human IL17A in direct ELISAs.

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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