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Research Grade tolododekin alfa (HV282016)

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Overview
Catalog No.HV282016
Description
tolododekin alfa (HV282016) is a research-grade recombinant antibody targeting IL12RB2.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
Species reactivityHuman
ApplicationsFunctional assay
IsotypeIL12RB2
Clonality Monoclonal
Target IL12RB2
Endotoxin level < 10 EU/mg
Purity >95% as determined by SDS-PAGE
Purification Protein A/G purified from cell culture supernatant.
Accession Q99665
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesCAS: 3028474-00-9
Background

Interleukin-12 receptor subunit beta-2 is a ~97 kDa protein. Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production.

Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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