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Anti-Human CD200R1 Reference Antibody (Ucenprubart, RUO) (HV213046)

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Anti-Human CD200R1 Reference Antibody (Ucenprubart, RUO)

Anti-Human CD200R1 Reference Antibody (Ucenprubart, RUO)

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100ug
1mg

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Overview
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Datasheet
SDS

Overview

Catalog No.	HV213046
Description	Ucenprubart (HV213046) is a research-grade recombinant antibody targeting CD200. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Humanized
Isotype	IgG4-kappa
Expression system	Mammalian Cells
Clonality	Monoclonal
Target	MOX2R, Cell surface glycoprotein OX2 receptor 1, OX2R, Cell surface glycoprotein CD200 receptor 1, CD200R, CD200 cell surface glycoprotein receptor, CRTR2, CD200R1
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q8TD46
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	2414559-57-0
Background	Cell surface glycoprotein CD200 receptor 1 (CD200R1/OX2R) is a ~39 kDa protein. Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of pro-inflammatory molecules including TNF, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200.
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade Ucenprubart.

References

Datasheet

Anti-Human CD200R1 Reference Antibody (Ucenprubart, RUO).pdf

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Anti-Human CD200R1 Reference Antibody (Ucenprubart, RUO)