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Anti-Human PDGF-B Reference Antibody (Vasigrobart, RUO) (HF877026)

Anti-Human PDGF-B Reference Antibody (Vasigrobart, RUO)
Anti-Human PDGF-B Reference Antibody (Vasigrobart, RUO)
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  • Overview

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  • Datasheet

  • SDS

Overview
Catalog No.HF877026
Description
vasigrobart (HF877026) is a research-grade recombinant antibody targeting PDGFB.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
Species reactivityHuman
ApplicationsELISA, FCM, Functional assay
Host speciesHuman
ClonalityMonoclonal
IsotypeIgG4, kappa
Expression system Mammalian cells
Nature Recombinant
Target PDGFB
Endotoxin level < 10 EU/mg as determined by LAL method.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P01127
Form Liquid
Storage buffer 0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesCAS: 3030730-59-4
Background

Platelet-derived growth factor subunit B is a ~27 kDa protein. Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing.

1. Vanlandewijck, M. et al. (2015) PloS one 10, e0143407. PMID: 26599395
Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Human PDGF-B Reference Antibody (Vasigrobart, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade vasigrobart

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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