

| Catalog No. | HF877026 |
|---|---|
| Description |
vasigrobart (HF877026) is a research-grade recombinant antibody targeting PDGFB.
Highlights
|
| Species reactivity | Human |
| Applications | ELISA, FCM, Functional assay |
| Host species | Human |
| Clonality | Monoclonal |
| Isotype | IgG4, kappa |
| Expression system | Mammalian cells |
| Nature | Recombinant |
| Target | PDGFB |
| Endotoxin level | < 10 EU/mg as determined by LAL method. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P01127 |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | CAS: 3030730-59-4 |
| Background | Platelet-derived growth factor subunit B is a ~27 kDa protein. Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. 1. Vanlandewijck, M. et al. (2015) PloS one 10, e0143407. PMID: 26599395 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for Research Grade vasigrobart




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