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Anti-Human IL-6R alpha/IL6R & ALB Bispecific Reference Antibody (Vobarilizumab, RUO) (HY583066)

Anti-Human IL-6R alpha/IL6R & ALB Bispecific Reference Antibody (Vobarilizumab, RUO)
Anti-Human IL-6R alpha/IL6R & ALB Bispecific Reference Antibody (Vobarilizumab, RUO)
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Overview
Catalog No.HY583066
Description
Vobarilizumab (HY583066) is a research-grade recombinant antibody targeting CD126. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHuman
IsotypeVH-VH'
Expression system Mammalian cells
Clonality Monoclonal
Target sIL6R, Interleukin-6 receptor subunit alpha, CD126, IL-6R 1, IL-6R subunit alpha, Membrane glycoprotein 80, gp80, IL6R, IL-6RA, IL-6 receptor subunit alpha, IL-6R-alpha, ALB, Albumin
Endotoxin level < 10 EU/mg
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P08887 & P02768
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesBispecific, (20A11-9mer-ALB11), ALX-0061, 1628814-88-9
BackgroundVobarilizumab (ALX-0061) is a humanized bispecific anti-IL-6R and anti-human serum albumin (ALB) monoclonal antibody (mAb) (Kd: 0.19 pM). Vobarilizumab consists of an anti-IL-6R domain and an anti-human serum albumin domain. Vobarilizumab can be used in the research of inflammatory autoimmune diseases, such as rheumatoid arthritis.
Note For research use only. Not suitable for clinical or therapeutic use.
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  • Anti-Human IL-6R alpha/IL6R & ALB Bispecific Reference Antibody (Vobarilizumab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Vobarilizumab

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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