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Anti-Human FGFR3 Reference Antibody (Vofatamab, RUO) (HB665016)

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Anti-Human FGFR3 Reference Antibody (Vofatamab, RUO)

Anti-Human FGFR3 Reference Antibody (Vofatamab, RUO)

Anti-Human FGFR3 Reference Antibody (Vofatamab, RUO)

Anti-Human FGFR3 Reference Antibody (Vofatamab, RUO)

Anti-Human FGFR3 Reference Antibody (Vofatamab, RUO)

Anti-Human FGFR3 Reference Antibody (Vofatamab, RUO)

Anti-Human FGFR3 Reference Antibody (Vofatamab, RUO)

Anti-Human FGFR3 Reference Antibody (Vofatamab, RUO)

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100ug
1mg

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Overview
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References
Datasheet
SDS

Overview

Catalog No.	HB665016
Description	Vofatamab (HB665016) is a research-grade recombinant antibody targeting CD333. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Humanized
Isotype	IgG1-kappa
Expression system	Mammalian Cells
Clonality	Monoclonal
Target	Fibroblast growth factor receptor 3, FGFR-3, FGFR3, JTK4, CD333
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P22607
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names	MFGR1877S, MFGR-1877S, MFGR1877S, 1312305-12-6
Background	Fibroblast growth factor receptor 3 (CD333/FGFR3) is a ~87 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis. Plays an essential role in the regulation of chondrocyte differentiation, proliferation and apoptosis, and is required for normal skeleton development. Regulates both osteogenesis and postnatal bone mineralization by osteoblasts. Promotes apoptosis in chondrocytes, but can also promote cancer cell proliferation. Required for normal development of the inner ear.
Note	For research use only. Not suitable for clinical or therapeutic use.

Images

SEC-HPLC

SEC-HPLC detection for Research Grade Vofatamab.
Bioactivity

Detects CD333/FGFR3 in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Vofatamab.
Western blot

Western blot analysis was performed using anti-CD333/FGFR3 monoclonal antibody at 1μg/ml on various samples.
Lane 1: recombinant human CD333/FGFR3 (Catalog No: HB665011)

References

Datasheet

Anti-Human FGFR3 Reference Antibody (Vofatamab, RUO).pdf

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Anti-Human FGFR3 Reference Antibody (Vofatamab, RUO)