Anti-Human IGF-I/IGF-1 Reference Antibody (Xentuzumab, RUO) (HY095016)

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100ug
1mg

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Overview

Catalog No.	HY095016
Description	Research Grade Xentuzumab (HY095016) is a humanized monoclonal antibody detecting IGF-I in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human. Highlights ●Multi-Application — Validated across multiple applications.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Humanized
Isotype	IgG1-lambda
Expression system	Mammalian Cells
Species	Human
Clonality	Monoclonal
Target	IGF-I, IGF1, Mechano growth factor, MGF, Insulin-like growth factor I, IBP1, Somatomedin-C, IGF2, IGF-II, Insulin-like growth factor II, T3M-11-derived growth factor, Somatomedin-A
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P05019 & P01344
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternate Names	BI 836845, 1417158-65-6
Background	Xentuzumab (Anti-Human IGF1 and IGF2 Recombinant Antibody; BI836845) is a recombinant a human monoclonal antibody that targets IGF ligands IGF1 and IGF2. Xentuzumab inhibits both of IGF1 and IGF2 growth-promoting signalling and suppresses AKT activation.
Note	For research use only. Not suitable for clinical or therapeutic use.

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Bioactivity

Detects IGF1 in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Xentuzumab.

References

Datasheet

Anti-Human IGF-I/IGF-1 Reference Antibody (Xentuzumab, RUO).pdf

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Recombinant Proteins

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Anti-Human IGF-I/IGF-1 Reference Antibody (Xentuzumab, RUO) (HY095016)

Overview

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References

Datasheet

SDS

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