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Anti-Human MASP3/MASP1 Reference Antibody (Zaltenibart, RUO) (HW369016)

Anti-Human MASP3/MASP1 Reference Antibody (Zaltenibart, RUO)
Anti-Human MASP3/MASP1 Reference Antibody (Zaltenibart, RUO)
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Overview
Catalog No.HW369016
Description
Zaltenibart (HW369016) is a research-grade recombinant antibody targeting Mannose-binding lectin-associated serine protease 1. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesChimeric
IsotypeIgG4-kappa
Expression system Mammalian cells
Clonality Monoclonal
Target Mannose-binding lectin-associated serine protease 1, CRARF, PRSS5, CRARF1, Mannose-binding protein-associated serine protease, Ra-reactive factor serine protease p100, Complement factor MASP-3, RaRF, MASP1, Mannan-binding lectin serine protease 1, Serine protease 5, Complement-activating component of Ra-reactive factor, MASP-1
Endotoxin level < 10 EU/mg
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P48740
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names2527079-60-1
Background

Mannan-binding lectin serine protease 1 (MASP1) is a ~79 kDa protein. Precursor of a serum protease that activates the complement pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system.

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Human MASP3/MASP1 Reference Antibody (Zaltenibart, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Zaltenibart.

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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