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Anti-Human GAS6 Reference Antibody (KM5320, RUO) (HC347026)

Anti-Human GAS6 Reference Antibody (KM5320, RUO)
Anti-Human GAS6 Reference Antibody (KM5320, RUO)
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Overview
Catalog No.HC347026
Description
Anti-Human GAS6 (KM5320) (HC347026) is a research-grade recombinant antibody targeting AXLLG. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesMouse
ClonalityMonoclonal
IsotypeIgG1
Clone IDKM5320
Expression system Mammalian cells
Target AXLLG, Growth arrest-specific protein 6, AXL receptor tyrosine kinase ligand, GAS6, GAS-6
Endotoxin level < 10 EU/mg
Purity >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q14393
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Growth arrest-specific protein 6 (GAS6) is a ~74 kDa protein. Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.

Note For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207)
Images
  • Anti-Human GAS6 Reference Antibody (KM5320, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Anti-Human GAS6 (KM5320).

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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