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In Vivo Antibodies

abinScience in vivo antibodies are functional-grade reagents optimized for animal studies—azide-free, low endotoxin, sterile-filtered and aggregation-tested. Available in blocking, depleting, and neutralizing formats with lot-specific CoA reporting purity, endotoxin (LAL), and sterility. Includes IgG, F(ab')2, and Fc-engineered options. RUO

Why Researchers Choose abinScience

Animal-Compatible Azide-free, carrier-free, sterile buffer
Low Endotoxin LAL-tested, ≤0.1 EU/μg typical
Aggregation Control SEC-HPLC/DLS verified
Flexible Formats IgG, F(ab')2, Fc variants
Lot-Specific QC CoA with endotoxin, purity, sterility

Shop by Function

Shop by Application

Selection & Handling Guide

  1. Function: Select blocking, depleting, or neutralizing based on target and desired MoA.
  2. Format: Choose IgG for Fc-mediated effects (ADCC/CDC); F(ab')2 to eliminate FcγR binding.
  3. Dosing: Follow mg/kg guidelines from literature; common routes: i.p., i.v., s.c.
  4. QC Review: Check lot CoA for endotoxin, purity, and sterility before use.
  5. Controls: Always include matched isotype and vehicle controls.

Applications

Immunotherapy mechanism studies
Cell depletion in vivo
Cytokine blockade in disease models
Vaccine efficacy and immune modulation

Documents & QC

Lot-specific CoA: concentration, endotoxin, purity, sterility
Aggregation data (SEC-HPLC/DLS)
Recommended dosing and handling protocols

FAQs

How is an in vivo antibody different from standard lab grade?

In vivo products are azide-free, low endotoxin, sterile-filtered and aggregation-controlled, with carrier-free buffers and lot-level QC tailored to animal studies.

Should I choose IgG or F(ab')2?

Use IgG for Fc effector functions (depletion/engagement); use F(ab')2 when avoiding FcγR interactions is important.

Recommended endotoxin level?

Select low-endotoxin lots per protocol and record values from the lot-specific CoA; control endotoxin alongside dose and route.

Can these be used in humans?

No. All products are for Research Use Only (RUO) and not intended for diagnostic or therapeutic use.

What is InVivo Plus?

InVivo Plus is abinScience’s premium functional-grade specification with defined buffer, endotoxin and aggregation criteria; see the dedicated page for details.

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    Antibodies (510)
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    CD3E (2)
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    PF45/48 (2)
    IL6R (1)
    IL9 (1)
    Outer capsid glycoprotein VP7 (1)
    CD115/CSF1R (1)
    PSCA (1)
    CXCL9/MIG (1)
    ACE2 (2)
    IL13 (1)
    Blood group Hantigen/Globo H (3)
    FAP/FAPalpha (1)
    Pvs25 (1)
    Mature virion in Complex [(VP0/1/3)5]12 (2)
    CDH17/Cadherin-17 (1)
    entB/SEB (1)
    CD335/NCR1/NKp46 (1)
    IL22 (1)
    gB/BALF4 (2)
    EGFL7 (1)
    Capsid protein VP1 (2)
    HBsAg (5)
    Fusion glycoprotein/F Trimer (1)
    IL1B/IL1F2 (1)
    S2 Protein (1)
    CSF1/M-CSF (1)
    IFNAR1 (1)
    STAT3 (1)
    GDF11/BMP11 (1)
    S/Spike glycoprotein (1)
    IFNB1/IFN-beta (1)
    Envelope protein E (7)
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    botA/BoNT (2)
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    IL2 (1)
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    IGF1 (2)
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    shiga toxin type 1B/stx1B (1)
    IL5 (1)
    NGF/Beta-NGF (2)
    CD279/PD-1 & CD47/MER6 (1)
    CCL8/MCP-2 (1)
    VSIG4/CRIg (1)
    IL31RA (1)
    IFNG/IFN-gamma (2)
    BDNF (1)
    RAGE/AGER (3)
    gE/Envelope glycoprotein E (1)
    HA/Hemagglutinin (7)
    cyaA/Cyclolysin (2)
    IGF2 (1)
    ADAMTS4 (4)
    F2/Prothrombin/PIVKA-II (1)
    CD268/TNFRSF13C (2)
    CD314/KLRK1 & CD3E (1)
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    CD279/PD-1 (8)
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    VSIR/VISTA & CD274/PD-L1 (1)
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    Spike glycoprotein 2 (5)
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    CD228/MELTF (1)
    ADGRE1/F4/80 & CD3E (1)
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    CD274/PD-L1 & CD3E (1)
    CD274/PD-L1 (5)
    ProteinUL128 & UL131A (1)
    gB/UL27 (1)
    IL11RA (2)
    L3/CP-H/Protein II (1)
    IL23A (1)
    TPSAB1/Tryptase-1 (1)
    IL21 (1)
    CD276/B7-H3 & CD3E (1)
    CX3CL1/Fractalkine (1)
    LRRC15/LIB (1)
    IFNA1/Interferon alpha-D (1)
    CCL17/TARC (1)
    CD274/PD-L1 & CD47/MER6 (1)
    PDGFB (1)
    CDH11 (1)
    CSF3/G-CSF (1)
    Toxin A/tcdA (1)
    BMP6 (1)
    pro-MSTN/GDF8 (1)
    CD37/TSPAN26 (1)
    CD132/IL2RG (1)
    TGFB2/TGF-beta-2 (1)
    IFN α2/IFNA2 (1)
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    Procapsid [(VP0/1/3) 5] 12 (2)
    F9/Factor IX (1)
    NP/Nucleoprotein (3)
    CD200 & CD47/MER6 (1)
    VEGFA (1)
    Spike glycoprotein (1)
    Protein prM/prM (3)
    S2/Spike protein S2' (1)
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    Galectin-3/Gal-3 (1)
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    CXCL12/SDF-1 (1)
    IL20 (1)
    HSP90 (1)
    GPA33 (1)
    HLA-A*11:01 (1)
    Intermediate capsid protein VP6 (1)
    CCL24/Eotaxin-2/MPIF-2 (1)
    Capsid protein VP25 (1)
    SSEA4 (4)
    gH/gL Complexes (2)
    CD79B & CD3E (1)
    SOST (1)
    IL36RN/IL-1F5/IL-36Ra (1)
    IL31 (4)
    KLKB1/KLK3 (1)
    env/Envpolyprotein (1)
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    CD52 (1)
    CD295/LEPR (1)
    RBD (13)
    CD198/CCR8 (2)
    GP/Envelopment polyprotein (1)
    env/Env polyprotein (4)
    CD274/PD-L1 & CD134/OX40 (1)
    CD49d/ITGA4 (1)
    Fluorescein & CD3E (1)
    CD152/CTLA4 & CD274/PD-L1 (1)
    TRP-1 & CD47/MER6 (1)
    CDH1/CDH11 (1)
    Flt3 ligand/FLT3LG (1)
    GP1 glycoprotein (2)
    F/Fusion glycoprotein F0 (8)
    ADAMTS5 (2)
    Capsid protein VP2 (1)
    TRP-1 & CD3e (1)
    TGFA/TGF-alpha (1)
    CNR1/CB1 (3)
    HBEGF (1)
    iga/IgA1 protease (1)
    GDF2/BMP9 (1)
    WNT2 (2)
    mature virion in complex (5)
    gH/Envelope glycoprotein H (2)
    E1 & E2 (gp35 & gp70) (3)
    IL11 (2)
    NS1/Non-structural protein 1 (1)
    TGFB1 (2)
    TIGIT & CD274/PD-L1 (1)
    LRP6 (1)
    ACVRL1/ALK-1 & VEGFA (1)
    BMP10 (1)
    GPC (1)
    gB/Envelope glycoprotein B (8)
    ERBB3/HER3 (1)
    CD20/MS4A1 (1)
    S1 N-terminal domain/S1-NTD (1)
    CA9 (1)
    FOLH1/PSMA (1)
    gD/Envelope glycoprotein D (2)
    F12/Coagulationfactor XII (1)
    CCL5/RANTES (1)
    RSPO3 (1)
    Fusion glycoprotein F0 (4)
    DPEP3 (1)
    GIPR/GIP-R (2)
    Glycoprotein G (6)
    gH/UL75 (1)
    MUC16/CA-125 (1)
    VWF (1)
    Capsid protein (2)
    G/Major surface glycoprotein G (2)
    CD137/4-1BB (2)
    CD254/RANKL/TNFSF11 (1)
    EPO (1)
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    ATTR/Transthyretin amyloidosis (4)
    L1/Major capsid protein L1 (2)
    Tityustoxin VII/Toxin VII/Ts7 (1)
    NS1/gp68/gp70 (6)
    CD283/TLR3 (2)
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    APOE4 (1)
    L2/Minor capsid protein L2 (2)
    APCS/PTX2 (1)
    gp125 (1)
    CXCL11/I-TAC (1)
    CD99 (1)
    OSM/Oncostatin-M (1)
    ADM/Adrenomedullin (1)
    CD73/NT5E (2)
    CD40/TNFRSF5 (1)
    CXCL4/PF4 (1)
    CCL3/MIP-1-alpha (1)
    CCL11/Eotaxin (1)
    ENT2/SLC29A2 (1)
    CD152/CTLA4 (2)
    ANGPTL3 (1)
    RBD (S6P trimer) (3)
    IL17A (4)
    CD274/PD-L1 & CD28 (1)
    PTP4A1/PRL1 (1)
    aPC/Activated protein C (3)
    FCGRT/FCRN (1)
    lukF (1)
    CD152/CTLA4 & CD134/OX40 (1)
    CD8a/Lyt2 (1)
    CSPG4/HMW-MAA/MCSP (1)
    PAUF (1)
    Major surface glycoprotein G (3)
    Pre-F/Fusion glycoprotein F0 (2)
    GPRC5D (1)
    TREM1 & CD46 (1)
    CD16/CD32 (1)
    shiga toxin type 2A/stx2A (1)
    EGFR/ERBB1 & CD3E (1)
    SOD1 (1)
    CCL1/I-309 (1)
    AFP/Alpha-fetoprotein (1)
    CTGF/CCN2 (1)
    Neuraminidase/NA (3)
    Fusion glycoprotein (4)
    BMP4 (1)
    gp120/Glycoprotein 120 (1)
    STEAP1 (1)
    TNFSF9/4-1BBL (2)
    Heparanase (1)
    CD16a/FCGR3A (3)
    APOE3/4 (1)
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    C1S (1)
    RBD (Omicron/JN.1) (2)
    FedF (1)
    IL12B/IL-12 p40 (1)
    Prefusion Protein (2)
    NA/Neuraminidase (1)
    CLDN3/Claudin-3 (1)
    FGF21 (1)
    VP1/Coatprotein VP1 (2)
    CD307e/FCRL5 (1)
    PRLR (1)
    TCRαβ/alpha-beta TCR (1)
    ANGPTL4 (2)
    shiga toxin type 2/stx2B (1)
    GP/Glycoprotein (5)
    CD122/IL2RB (1)
    CD340/ERBB2 (1)
    PDGFC (1)
    Major capsid protein L1 (3)
    LGR5/GPR49 (1)
    EGFRvIII & CD3E (1)
    F8/Coagulation factor VIII (7)
    wlaB/pglK (1)
    CD20/MS4A1 & CD3E (1)
    IL8/CXCL8 (1)
    CCL2/MCP-1 (1)
    MUC5AC (1)
    ROR1/NTRKR1 (1)
    CCL14/NCC-2 (1)
    APOE2/3/4 (1)
    IL10 (1)
    Outer capsid protein VP4 (2)
    IL18/IL1F4 (1)
    BTN3A (1)
    IL17F (1)
    GDF15/MIC1 (1)
    Toxin B/tcdB (1)
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    Protease/PR (1)
    CXCL1/NAP-3/GRO-alpha (1)
    TSG101 (2)
    CD4 (1)
    ERVW-1/HERV-W-Env (1)
    SFRP1 (1)
    CD110/TPOR (2)
    VLP (1)
    CD120b/TNFR2 (1)
    BAG3 (1)
    SNCA/Alpha-synuclein (5)
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    Fc Block (1)
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    FAP & CD3E (1)
    Glycoprotein C/Gc (2)
    LTA/TNF-beta (1)
    LAMP5 (1)
    PTP4A3/PRL3 (1)
    gp140/Env Trimer (2)
    CD340/ERBB2 & CD3E (2)
    CD279/PD-1 & CD274/PD-L1 (1)
    RBP2b (1)
    TREML1/TLT1 (1)
    MSLN/Mesothelin (1)
  • Species
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    Bordetella pertussis (2)
    Mouse (65)
    Bundibugyo ebolavirus (BDBV) (1)
    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (21)
    Monkey (1)
    Human adenovirus 3 (HAdV-3) (1)
    Human herpesvirus 1 (HSV-1/HHV-1) (5)
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    Ebola virus (EBOV) (1)
    Human cytomegalovirus (HCMV/HHV-5) (7)
    Enterovirus 71 (EV71) (4)
    Hantaan virus (HTNV) (2)
    Tai Forest ebolavirus (TAFV) (1)
    Hepatitis E virus/HEV (1)
    Candida albicans (1)
    Cat (1)
    Human astrovirus-8 (HAtVs) (1)
    Varicella-zoster virus (VZV/HHV-3) (4)
    Dog (11)
    Dengue virus type 3 (DENV-3) (1)
    Middle East respiratory syndrome-related coronavirus (MERS-CoV) (5)
    Zika virus (ZIKV) (2)
    Orthohantavirus puumalaense (PUUV) (1)
    Sudan ebolavirus (SEBOV) (1)
    Machupo virus (MACV) (1)
    Human respiratory syncytial virus (HRSV) (14)
    Human hepatitis A virus (HHAV) (1)
    Puumala virus (PUUV) (2)
    Streptococcus pneumoniae (1)
    Coxsackievirus A16 (CVA16) (2)
    Human parvovirus B19 (HPV B19) (3)
    Nipah virus (NiV) (13)
    Dengue virus type 4 (DENV-4) (1)
    Lassa virus (LASV) (1)
    Bovine respiratory syncytial virus (BRSV) (2)
    Dobrava-Belgrade virus (DOBV) (2)
    Human betacoronavirus 2c EMC/2012 (HCoV-EMC) (2)
    Human papillomavirus 6 (HPV6) (1)
    Porcine circovirus 2 (PCV2) (2)
    Brazilian scorpion (1)
    Hepatitis C Virus (HCV) (9)
    Human papillomavirus 16 (HPV16) (2)
    Rabbit (2)
    Staphylococcus aureus (3)
    Seoul virus (SEOV) (2)
    Human metapneumovirus (2)
    Rat (1)
    Human metapneumovirus (HMPV) (5)
    Human immunodeficiency virus 1 (HIV-1) (10)
    Hepatitis B virus genotype A (HBV-A) (6)
    E. coli (4)
    Japanese encephalitis virus (JEV) (1)
    Zaire ebolavirus (ZEBOV) (6)
    Andes virus (ANDV) (2)
    Human papillomavirus 58 (HPV58) (3)
    Severe acute respiratory syndrome coronavirus (SARS-CoV) (3)
    Campylobacter jejuni subsp. (1)
    Influenza B virus (Flu B) (1)
    Rotavirus (RV) (1)
    Hendra virus (HeV) (2)
    Clostridioides difficile (2)
    Human endogenous retroviruses W (HERV-W) (1)
    Human papillomavirus 59 (HPV59) (1)
    Chikungunya virus (CHIKV) (1)
    Human (224)
    Sin Nombre virus (SNV) (2)
    Coxsackievirus B1 (CBV1) (3)
    Rotavirus A (RV-A) (4)
    General (3)
    Plasmodium vivax (2)
    Epstein-Barr virus (EBV/HHV-4) (2)
    Poliovirus type 1 (PV1) (2)
    Plasmodium falciparum (2)
    Dengue virus type 2 (DENV-2) (9)
    Clostridium botulinum (2)
    Reston ebolavirus (REBOV) (1)
    Enterovirus D68 (EV-D68) (2)
    Junin mammarenavirus (JUNV) (1)
  • Applications
    0 selected
    FCM (77)
    Antagonist (1)
    IHC-F (3)
     ELISA (1)
    DB (2)
    in vivo research (1)
    WB (22)
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    FACS (2)
    ELISA (424)
    Cell Deplete (1)
    in vivo study (4)
    ICC (1)
    in vivo blocking of PD-1/PD-L signaling (2)
    Functional assay (2)
    Neutralization (388)
    FuncS (55)
    in vivo (1)
    T cell stimulation (Reported) (1)
    Research in vivo (2)
    in vivo PD-L1 blockade (3)
    in vivo CD4+ T cell depletion (1)
    Blocking (41)
    T cell depletion (Reported) (1)
    Agonist (8)
    in vitro PD-L1 blockade (3)
  • Reactivity
    0 selected
    Mouse (12)
    Puumala virus (1)
    Human (16)
    Influenza B virus (1)
    Chikungunya virus (1)
    Coxsackievirus B1 (CVB1) (3)
  • Host species
    0 selected
    Hamster (1)
    Alpaca (5)
    Mouse (161)
    Cat (1)
    Dog (8)
    Human (319)
    Rat (11)
  • Clonality
    0 selected
    Monoclonal (510)
  • Conjugate
    0 selected
    Unconjugated (510)

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